Relation of interleukin-1β gene to treatment response in chronic patients infected with HCV genotype 4 | Zendy

Moataza H Omran | Zendy; Noha E. Ibrahim | Zendy; Samar Samir Youssef | Zendy; Basma E Fatouh | Zendy; Wael Nabil | Zendy; Magdy M El-Shami | Zendy; Mostafa K. El Awady | Zendy

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Relation of interleukin-1β gene to treatment response in chronic patients infected with HCV genotype 4

Author(s) -

Moataza H Omran,

Noha E. Ibrahim,

Samar Samir Youssef,

Basma E Fatouh,

Wael Nabil,

Magdy M El-Shami,

Mostafa K. El Awady

Publication year - 2013

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.3823

Subject(s) - genotype , virology , immunology , medicine , gene , interleukin , biology , genetics , cytokine

Hepatitis C virus (HCV) infection results in chronic hepatitis in more than 70% of infected patients, while 20-30% of patients recover spontaneously. This strengthens the role of the host genetic factors in either spontaneous or drug-induced viral clearance. The aim of this study was to investigate the relationship between interleukin-1β +3953 gene polymorphism and the response to interferon therapy in chronic HCV patients infected with genotype 4.

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