Emergence of VIM-6 metallo-beta-lactamase-producing Alcaligenes faecalis clinical isolates in a hospital in India | Zendy

Atul Khajuria | Zendy; Ashok Kumar Praharaj | Zendy; Mahadevan Kumar | Zendy; Naveen Grover | Zendy

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Emergence of VIM-6 metallo-beta-lactamase-producing Alcaligenes faecalis clinical isolates in a hospital in India

Author(s) -

Atul Khajuria,

Ashok Kumar Praharaj,

Mahadevan Kumar,

Naveen Grover

Publication year - 2013

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.3556

Subject(s) - alcaligenes faecalis , microbiology and biotechnology , beta lactamase , alcaligenes , medicine , biology , bacteria , genetics , escherichia coli , gene , pseudomonas

Background Alcaligenes faecalis (A.faecalis) is a Gramnegative, rod-shaped, motile, oxidase, catalase and citrate positive obligate aerobe that is commonly found in the environment. A. faecalis is the most frequently isolated member of family Alcaligenaceae in the clinical laboratory. Infections caused by A. faecalis are opportunistic and are acquired from moist items such as nebulizers, respirators, and lavage fluid [1]. It has been reported to cause peritonitis, urinary tract infection (UTI), bacteremia and acute otitis media [1,2]. Although presence of PER-1 and TEM-21 Extended Spectrum Beta-Lactamases (ESBL) have been reported in clinical isolates of A. faecalis [3,4], carbapenem resistance has not yet been reported. This study aimed to investigate the mechanism of carbapenem resistance among clinical isolates of A. faecalis recovered from hospitalized patients in a tertiary care centre in Pune, India.

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