Molecular identification of the ompL1 gene within Leptospira interrogans standard serovars | Zendy

Mehrangiz Dezhbord | Zendy; Majid Esmaelizad | Zendy; Pejvak Khaki | Zendy; Fariba Fotohi | Zendy; Athena Zarehparvar Moghaddam | Zendy

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Molecular identification of the ompL1 gene within Leptospira interrogans standard serovars

Author(s) -

Mehrangiz Dezhbord,

Majid Esmaelizad,

Pejvak Khaki,

Fariba Fotohi,

Athena Zarehparvar Moghaddam

Publication year - 2014

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.3174

Subject(s) - leptospira , leptospirosis , serotype , leptospira interrogans , virology , gene , biology , recombinant dna , polymerase chain reaction , microbiology and biotechnology , genetics

Leptospirosis, caused by infection with pathogenic Leptospira species, is one of the most prevalent zoonotic diseases in the world. Current leptospiral vaccines are mainly multivalent dead whole-cell mixtures made of several local dominant serovars. Therefore, design and construction of an efficient recombinant vaccine for leptospirosis control is very important. OmpL1 is an immunogenic porin protein that could be of special significance in vaccination and serodiagnosis for leptospirosis.

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