Association of Mycobacterium avium subsp. paratuberculosis and SLC11A1 polymorphisms in Sardinian multiple sclerosis patients | Zendy

Davide Cossu | Zendy; Speranza Masala | Zendy; Eleonora Cocco | Zendy; Daniela Paccagnini | Zendy; Stefania Tranquilli | Zendy; Jessica Frau | Zendy; Maria Giovanna Marrosu | Zendy; Leonardo A. Sechi | Zendy

Open Access

Association of Mycobacterium avium subsp. paratuberculosis and SLC11A1 polymorphisms in Sardinian multiple sclerosis patients

Author(s) -

Davide Cossu,

Speranza Masala,

Eleonora Cocco,

Daniela Paccagnini,

Stefania Tranquilli,

Jessica Frau,

Maria Giovanna Marrosu,

Leonardo A. Sechi

Publication year - 2013

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.2737

Subject(s) - single nucleotide polymorphism , paratuberculosis , genotyping , snp , immunology , multiple sclerosis , biology , immune system , mycobacterium , snp genotyping , gene , population , disease , genotype , medicine , genetics , bacteria , environmental health

Recent findings propose that Mycobacterium avium subsp. paratuberculosis (MAP) infection could act as risk factor in favoring multiple sclerosis (MS) progression. SLC11A1 is a gene associated with mycobacterial survival in the host and it may be involved in the induction and maintenance of autoimmune disease.

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