Open AccessCharacteristics of the immune response during acute brucellosis in Sprague-Dawley rats
Author(s) -
Byeong Kirl Baek,
Mst. Minara Khatun,
Md. Ariful Islam,
Sung Il Lee
Publication year - 2009
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.248
Subject(s) - brucellosis , immune system , immunology , medicine
Brucella is a facultative, intracellular pathogen that causes severe disease in animals and humans. Immunity against Brucella involves both humoral and cellular responses. To investigate the characteristics of immune response in acute brucellosis in Sprague-Dawley (SD) rats, IgG and its subclass specific immunoglobulins' (IgG1 and IgG2a) response in sera against B. abortus biotype 1 infection were studied.
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