SPI-7: Salmonella’s Vi-Encoding Pathogenicity Island
Author(s) -
Helena M. B. Seth-Smith
Publication year - 2008
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.220
Subject(s) - pathogenicity island , salmonella enterica , virulence , salmonella , serotype , biology , typhoid fever , microbiology and biotechnology , virology , pathogenicity , gene , pilus , effector , transmission (telecommunications) , genetics , bacteria , immunology , electrical engineering , engineering
Salmonella Pathogenicity Island-7 (SPI-7) is a large, mosaic, genetic island, found in several serovars of Salmonella enterica subsp. enterica associated with systemic disease. As well as encoding genes which may aid its own transmission, it carries genes for potential virulence factors such as Vi antigen, SopE effector and type IVB pili. The stability of SPI-7 is of interest with respect to typhoid fever and related vaccines.
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