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Biomarkers in sepsis at time zero: intensive care unit scores, plasma measurements and polymorphisms in Argentina
Author(s) -
Silvia Daniela Amanda Perés Wingeyer,
Eleonora Cunto,
Cristina Mabel Nogueras,
Jorge Alejandro San Juan,
Norberto Ventura Gómez,
Gabriela de Larrañaga
Publication year - 2011
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.2108
Subject(s) - sepsis , intensive care unit , medicine , septic shock , gastroenterology , intensive care , plasminogen activator inhibitor 1 , sofa score , plasminogen activator , intensive care medicine
A patient's response to sepsis is influenced by their genetic background. Our objective was to use plasma markers, such as protein C (PC), D-dimer, Plasminogen Activator Inhibitor-1 (PAI-1) levels, and the PAI-1 rs1799889 4G/5G and  Tumor Necrosis Factor-α rs1800629 G/A  polymorphisms to improve classical intensive care unit (ICU) scores.

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