Utility of an interferon-gamma release assay as a potential diagnostic aid for active pulmonary tuberculosis | Zendy

Lynn Taki-Eddin | Zendy; Fawza Monem | Zendy

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Utility of an interferon-gamma release assay as a potential diagnostic aid for active pulmonary tuberculosis

Author(s) -

Lynn Taki-Eddin,

Fawza Monem

Publication year - 2011

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.2098

Subject(s) - medicine , gold standard (test) , interferon gamma release assay , interferon γ , tuberculosis , pulmonary tuberculosis , active tuberculosis , latent tuberculosis , tuberculosis diagnosis , mycobacterium tuberculosis , interferon gamma , pathology , cytokine

Sensitivity, specificity, early confirmation and obtaining an optimal specimen are challenging problems in active tuberculosis (TB) diagnosis. Interferon-gamma release assay (IGRA) is a good indicator for latent TB but can it be useful as a diagnostic tool for active TB? This study was designed to address these challenges and assess the potential of IGRA as a diagnostic indicator of active pulmonary TB by comparing it with other MT diagnostic conventional methods and molecular methods.

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