Open AccessGlucose-6-phosphate dehydrogenase status and severity of malarial anaemia in Nigerian children
Author(s) -
Adebola E. Orimadegun,
Olugbemiro Sodeinde
Publication year - 2011
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.1837
Subject(s) - glucose 6 phosphate dehydrogenase , glucose 6 phosphate dehydrogenase deficiency , dehydrogenase , medicine , biology , biochemistry , enzyme
Glucose-6-phosphate dehydrogenase (G6PD) deficiency (Gd-) contributes to morbidity and mortality in sub-Saharan Africa but recent data on the interaction between Gd- and malaria among children is scarce. We hypothesised that, being a haemolytic factor, Gd- makes severe malarial anaemia (SMA) more common and even more severe.
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