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Multidrug-resistant typhoid fever: a review
Author(s) -
Syed Ahmed Zaki,
Sunil Karande
Publication year - 2011
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.1405
Subject(s) - typhoid fever , medicine , ampicillin , public health , outbreak , salmonella typhi , ciprofloxacin , intensive care medicine , environmental health , antibiotics , virology , microbiology and biotechnology , biology , biochemistry , nursing , escherichia coli , gene
Multidrug-resistant typhoid fever (MDRTF) is defined as typhoid fever caused by Salmonella enterica serovar Typhi strains (S. Typhi), which are resistant to the first-line recommended drugs for treatment such as chloramphenicol, ampicillin and trimethoprim-sulfamethoxazole. Since the mid-1980s, MDRTF has caused outbreaks in several countries in the developing world, resulting in increased morbidity and mortality, especially in affected children below five years of age and those who are malnourished.

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