Dual infection with dengue virus 3 and human immunodeficiency virus 1 in Havana, Cuba
Author(s) -
María G. Guzmán,
Daniel Meseguer González,
Daniel Limonta,
Juan Bandera,
Jorge Pérez,
Gustavo Kourí
Publication year - 2009
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.131
Subject(s) - dengue fever , virology , dengue virus , serology , incidence (geometry) , human immunodeficiency virus (hiv) , medicine , virus , disease , viral disease , immunology , antibody , physics , optics
Although dengue virus (DEN) endemic regions overlap with human immunodeficiency virus 1 (HIV) high incidence areas, little has been documented on HIV and DEN mixed infection. Here we report DEN/HIV concurrent infections recorded during the DEN-3 epidemic in 2001-2002 in Havana. Serologic-confirmed DEN is described in two HIV-infected subjects with dengue fever symptoms. Although patients had dengue disease, the CD4+ cells remained within normal levels and no accelerated progression of HIV disease was observed. To our knowledge, DEN cases caused by DEN-3 in HIV-infected individuals have not been reported previously. Further research is needed to diagnose this likely underreported mixed viral infection in DEN endemic areas.
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