Toxoplasma gondii destroys Her2/Neu-expressing mammary cancer cells in vitro using a continuous feed medium approach | Zendy

Esra Atalay Şahar | Zendy; Mert Döşkaya | Zendy; Muhammet Karakavuk | Zendy; Hüseyin Can | Zendy; Aytül Gül | Zendy; Adnan Yüksel Gürüz | Zendy; Aysu Değirmenci Döşkaya | Zendy; Levent Yenıay | Zendy

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Toxoplasma gondii destroys Her2/Neu-expressing mammary cancer cells in vitro using a continuous feed medium approach

Author(s) -

Esra Atalay Şahar,

Mert Döşkaya,

Muhammet Karakavuk,

Hüseyin Can,

Aytül Gül,

Adnan Yüksel Gürüz,

Aysu Değirmenci Döşkaya,

Levent Yenıay

Publication year - 2020

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.12820

Subject(s) - toxoplasma gondii , laboratory flask , biology , in vitro , inoculation , cancer , cancer cell , cell culture , virology , immunology , chemistry , genetics , antibody

Toxoplasma gondii is an opportunistic protozoan and can be grown using several human cell lines. Breast cancer is the second leading cause of cancer death in women. Her2/Neu-expressing mammary cancer cell lines called TUBO can be grown in vitro. In recent years, protozoan parasites have become popular means of use in cancer therapy research. In this study, we analyzed whether T. gondii tachyzoites can destroy TUBO cells using a novel continuous feed medium approach.

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