Oral melatonin improves the detection of parasitemia in malaria
Author(s) -
Chandan Kumar Kedarisetty,
B Laksminarayana Samaga,
Sudha Vidyasagar,
Jayanthi Venkataraman
Publication year - 2020
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.12518
Subject(s) - melatonin , parasitemia , malaria , medicine , placebo , clinical endpoint , gold standard (test) , clinical trial , gastroenterology , plasmodium falciparum , immunology , pathology , alternative medicine
Malaria is a growing global threat and a major cause of mortality in the tropics. The gold standard diagnosis is peripheral blood smear examination. It has been demonstrated that melatonin acts as messenger molecule in malaria pathophysiology. This concept was used to evolve a clinical study wherein use of exogenous melatonin could improve the chance of detection of the parasite.
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