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Frequency and genotype distribution of high risk human papillomavirus in esophageal squamous cell carcinoma
Author(s) -
Nuzhat Sultana,
Walayat Shah,
Waheed Iqbal,
Shahid Pervez,
Ikramullah Khan,
Mohammad Hanif,
Imran Khan
Publication year - 2020
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.12487
Subject(s) - genotype , polymerase chain reaction , medicine , human papillomavirus , incidence (geometry) , esophageal squamous cell carcinoma , disease , oncology , risk factor , virology , gastroenterology , carcinoma , biology , gene , genetics , physics , optics
Esophageal squamous cell carcinoma (ESCC) is a dismal disease exhibiting striking geographical differences in its incidence. It is multifactorial in origin. Among infectious agents, human papillomavirus (HPV) was introduced as a possible causative agent in the development of ESCC in 1982. Subsequent studies using various methods have confirmed the presence of HPV in ESCC. We aimed to determine the frequency of HPV in ESCC in northwest Pakistan which is part of high risk belt for this disease.

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