Increased serum antimicrobial peptide LL-37 and HBD-2 combined with 25-hydroxyvitamin D3 deficiency in infants with pertussis | Zendy

Sihu Chen | Zendy; Wanding Ye | Zendy; Weikun Zheng | Zendy; Zhiwei Xu | Zendy; Yiping Chen | Zendy; Longteng Jin | Zendy

Open Access

Increased serum antimicrobial peptide LL-37 and HBD-2 combined with 25-hydroxyvitamin D3 deficiency in infants with pertussis

Author(s) -

Sihu Chen,

Wanding Ye,

Weikun Zheng,

Zhiwei Xu,

Yiping Chen,

Longteng Jin

Publication year - 2020

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.12317

Subject(s) - medicine , vitamin d deficiency , cathelicidin , vitamin d and neurology , pertussis toxin , immune system , immunology , endocrinology , gastroenterology , g protein , receptor , innate immune system

Most children with serious infection diseases suffer from malnutrition. Vitamin D participates in the immune response through endogenous antimicrobial peptides (AMPs) regulation. The aim of this study is to investigate the expression of 25-hydroxyvitamin D3 [25(OH)D3], AMPs [LL-37 and human β-defensin 2 (HBD-2)] in the children with pertussis.

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