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Increased systemic sST2 in patients with end stage renal disease contributes to milder liver damage during HCV infection
Author(s) -
Ružica Lukić,
Maja Ćupić,
Nevena Gajović,
Milena Jurišević,
Željko Mijailović,
Bojana Davidović,
Bojan Kujundžić,
Bojan Joksimović,
Nebojša Arsenijević,
Ivan Jovanović
Publication year - 2020
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.11741
Subject(s) - end stage renal disease , medicine , liver disease , gastroenterology , stage (stratigraphy) , disease , liver damage , immunology , biology , paleontology
Hepatitis C Virus (HCV) is the leading cause of chronic liver disease and is a serious global health problem. Hepatitis C infection is highly prevalent in patients with end stage renal disease (ESRD), due to frequent exposure to blood and blood products, nosocomial transmission of HCV, and prolong hemodialysis duration. The aim of the study was to evaluate the influence of IL-33/ST2 signaling pathway on severity of the liver disease in ESRD HCV+ patients.

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