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Epidemiology of Cytomegalovirus among pregnant women in Africa
Author(s) -
Doreen Mhandire,
Sarah Rowland–Jones,
Kudakwashe Mhandire,
Mamadou Kaba,
Collet Dandara
Publication year - 2019
Publication title -
the journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.11373
Subject(s) - cytomegalovirus , seroprevalence , medicine , pregnancy , transmission (telecommunications) , epidemiology , obstetrics , human cytomegalovirus , immunology , pediatrics , demography , serology , human immunodeficiency virus (hiv) , viral disease , antibody , herpesviridae , virus , biology , sociology , electrical engineering , genetics , engineering
Vertical transmission of Cytomegalovirus (CMV), resulting in congenital CMV (cCMV) infection could have disabling and potentially fatal effects on the foetus or neonate. Although primary infection probably has a higher risk of leading to cCMV, in highly seropositive populations, a significant risk of vertical transmission is thought to be due to CMV reactivation and or reinfection during pregnancy. In this narrative review, we summarise the prevalence of CMV infection and associated risk factors among pregnant African women, in a setting where primary CMV infection usually occurs during infancy.

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