Presence of blaCTX-M antibiotic resistance gene in Lactobacillus spp. isolated from Hirschsprung diseased infants with stoma | Zendy

Umama Khan | Zendy; Sadia Afsana | Zendy; Maria Kibtia | Zendy; Mahboob Hossain | Zendy; N. Choudhury | Zendy; Chowdhury Rafiqul Ahsan | Zendy

Open Access

Presence of blaCTX-M antibiotic resistance gene in Lactobacillus spp. isolated from Hirschsprung diseased infants with stoma

Author(s) -

Umama Khan,

Sadia Afsana,

Maria Kibtia,

Mahboob Hossain,

N. Choudhury,

Chowdhury Rafiqul Ahsan

Publication year - 2019

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.10968

Subject(s) - microbiology and biotechnology , antibiotics , biology , lactobacillus , antibiotic resistance , cephalosporin , pathogenic bacteria , aztreonam , bacteria , genetics , imipenem

Although antibiotics have revolutionized health care by saving lives, the evolution of both pathogenic and commensal antibiotic-resistant bacteria are emerging as a threat in the health sector. As for Lactobacillus spp., it is usually a non-pathogenic bacteria. However, it can cause infection in immunocompromised condition. In this study, Lactobacillus spp. has been isolated from the faeces of infants with Hirschsprung disease (HD), which is congenital aganglionosis of intestine, where surgical approach and antibiotics are frequently used as medical intervention. The aim of this study is to assess the antibiotic resistance pattern and determine the presence of resistance genes, if any, in Lactobacillus spp. isolated from HD infants with ileostomy.

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