Antibacterial effect of acrylic bone cements loaded with drugs of different action’s mechanism | Zendy

Lizette Morejón Alonso | Zendy; Iran Fernández Torres | Zendy; Ángela M Zayas Tamayo | Zendy; O. Lozano | Zendy; Ivette Durán Ramos | Zendy; José Ángel Delgado GarcíaMenocal | Zendy; Nely Ríos-Donato | Zendy; Eduardo Mendizábal | Zendy

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Antibacterial effect of acrylic bone cements loaded with drugs of different action’s mechanism

Author(s) -

Lizette Morejón Alonso,

Iran Fernández Torres,

Ángela M Zayas Tamayo,

O. Lozano,

Ivette Durán Ramos,

José Ángel Delgado GarcíaMenocal,

Nely Ríos-Donato,

Eduardo Mendizábal

Publication year - 2019

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.10716

Subject(s) - mechanism (biology) , action (physics) , materials science , philosophy , physics , epistemology , quantum mechanics

Antibiotic-loaded bone cements of poly(methyl methacrylate) are considered as very useful biomaterials for the management of corporal deep osseous infections. However, the high prevalence of resistant germs and polymicrobial infections makes it necessary to search for new formulations of bone cements containing antibiotics for local antibacterial therapy. In this work, bone cements loaded with drugs with different mechanism of action were evaluated to determine its antibacterial effectiveness on Pseudomonas aeruginosa.

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