Anti-Human Herpesvirus 8 antibodies affect both insulin and glucose uptake by virus-infected human endothelial cells | Zendy

Fabrizio Angius | Zendy; Enrica Piras | Zendy; Stefano Spolitu | Zendy; Luisa Marras | Zendy; Sara Federica Armas | Zendy; Angela Ingianni | Zendy; Pierpaolo Contini | Zendy; Raffaello Pompei | Zendy

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Anti-Human Herpesvirus 8 antibodies affect both insulin and glucose uptake by virus-infected human endothelial cells

Author(s) -

Fabrizio Angius,

Enrica Piras,

Stefano Spolitu,

Luisa Marras,

Sara Federica Armas,

Angela Ingianni,

Pierpaolo Contini,

Raffaello Pompei

Publication year - 2018

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.10381

Subject(s) - insulin , antibody , glucose uptake , carbohydrate metabolism , immunofluorescence , biology , endothelial stem cell , blot , kaposi's sarcoma , virology , immune system , cell culture , virus , in vitro , endocrinology , immunology , human herpesvirus , biochemistry , genetics , gene

Human Herpesvirus 8 (HHV8) is known to be the cause of the malignant tumour named Kaposi's sarcoma. It is believed to induce an intense modification of cell metabolism in endothelial cells. In this work we analysed the role of anti-HHV8 antibodies in both the insulin and glucose uptake of HHV8-infected primary human endothelial cells (HUVEC).

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