Diversity of Th1/Th2 immunity in mice with acute lung injury induced by the H1N1 influenza virus and lipopolysaccharides | Zendy

Jianxing Liu | Zendy; Ying Zhang | Zendy; Miao An | Zendy; Qingguang Wu | Zendy; Ya Chao Zhao | Zendy; Li Xiong | Zendy; Geng Li | Zendy

Open Access

Diversity of Th1/Th2 immunity in mice with acute lung injury induced by the H1N1 influenza virus and lipopolysaccharides

Author(s) -

Jianxing Liu,

Ying Zhang,

Miao An,

Qingguang Wu,

Ya Chao Zhao,

Li Xiong,

Geng Li

Publication year - 2019

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.10338

Subject(s) - virus , immunity , virology , immunology , influenza a virus , lung , biology , medicine , immune system

The polarization of T helper (Th) cells plays an important role in the inflammatory response, pathogen removal, and tissue damage processes of infectious acute lung injury (ALI). However, Th cell polarization in viral- or bacterial-mediated ALI is not well defined. Herein, an influenza virus (A/FM/1/47, H1N1) and lipopolysaccharide (LPS) were chosen to induce ALI in mice, and the resultant diversity of Th-cell polarization was explored.

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