Total lymphocyte count as a tool for timing opportunistic infection prophylaxis in resource-limited settings: a study from India | Zendy

Sreenivasan Srirangaraj | Zendy; D Venkatesha | Zendy

Open Access

Total lymphocyte count as a tool for timing opportunistic infection prophylaxis in resource-limited settings: a study from India

Author(s) -

Sreenivasan Srirangaraj,

D Venkatesha

Publication year - 2010

Publication title -

the journal of infection in developing countries

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.322

H-Index - 49

eISSN - 2036-6590

pISSN - 1972-2680

DOI - 10.3855/jidc.1011

Subject(s) - tuberculosis , medicine , human immunodeficiency virus (hiv) , lymphocyte , immunology , predictive value , opportunistic infection , limited resources , viral disease , pathology , risk analysis (engineering)

In resource-limited settings, due to the high cost of CD4 cell count testing, physicians must decide about opportunistic infection (OI) prophylaxis without a laboratory evaluation of HIV stage and level of immune suppression. This study aimed to evaluate the correlation of total lymphocyte count (TLC), an inexpensive laboratory parameter, to CD4 count, and to determine a range of TLC cut-offs for the initiation of OI prophylaxis that is appropriate for resource-limited settings.

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