Vitamin D Time Profile Based on the Contribution of Non-Genetic and Genetic Factors in HIV-Infected Individuals of European Ancestry
Author(s) -
Monia Guidi,
Giuseppe Foletti,
Paul J. McLaren,
Matthias Cavassini,
Andri Rauch,
Philip Tarr,
Olivier Lamy,
Alice Panchaud,
Amalio Telenti,
Chantal Csajka,
Margalida Rotger
Publication year - 2014
Publication title -
antiviral therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 87
eISSN - 2040-2058
pISSN - 1359-6535
DOI - 10.3851/imp2823
Subject(s) - vitamin d and neurology , darunavir , population , medicine , body mass index , cohort , single nucleotide polymorphism , pharmacokinetics , genotype , biology , human immunodeficiency virus (hiv) , genetics , viral load , immunology , antiretroviral therapy , gene , environmental health
Vitamin D deficiency is prevalent in HIV-infected individuals and vitamin D supplementation is proposed according to standard care. This study aimed at characterizing the kinetics of 25(OH)D in a cohort of HIV-infected individuals of European ancestry to better define the influence of genetic and non-genetic factors on 25(OH)D levels. These data were used for the optimization of vitamin D supplementation in order to reach therapeutic targets.
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