Antiviral Activity of Nucleoside Analogues against Norovirus | Zendy

Verónica Costantini | Zendy; Tony Whitaker | Zendy; Leslie Barclay | Zendy; David Lee | Zendy; Tamara R. McBrayer | Zendy; Raymond F. Schinazi | Zendy; Jan Vinjé | Zendy

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Antiviral Activity of Nucleoside Analogues against Norovirus

Author(s) -

Verónica Costantini,

Tony Whitaker,

Leslie Barclay,

David Lee,

Tamara R. McBrayer,

Raymond F. Schinazi,

Jan Vinjé

Publication year - 2012

Publication title -

antiviral therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.747

H-Index - 87

eISSN - 2040-2058

pISSN - 1359-6535

DOI - 10.3851/imp2229

Subject(s) - norovirus , virology , nucleoside , nucleoside analogue , reverse transcriptase inhibitor , didanosine , biology , medicine , virus , lamivudine , viral load , antiretroviral therapy , hepatitis b virus , genetics

Norovirus (NoV) is the leading cause of epidemic gastroenteritis worldwide. The lack of a cell culture has significantly hampered the development of effective therapies against human NoV. Clinically approved nucleoside and non-nucleoside analogues have been used successfully against RNA viruses.

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