Characterization of Aurintricarboxylic Acid as a Potent Hepatitis C Virus Replicase Inhibitor | Zendy

Ye Chen | Zendy; Alain Bopda Waffo | Zendy; Amartya Basu | Zendy; Ramalingam Krishnan | Zendy; Erica Silberstein | Zendy; Deborah R. Taylor | Zendy; Tanaji T. Talele | Zendy; Payal Arora | Zendy; Neerja KaushikBasu | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Characterization of Aurintricarboxylic Acid as a Potent Hepatitis C Virus Replicase Inhibitor

Author(s) -

Ye Chen,

Alain Bopda Waffo,

Amartya Basu,

Ramalingam Krishnan,

Erica Silberstein,

Deborah R. Taylor,

Tanaji T. Talele,

Payal Arora,

Neerja KaushikBasu

Publication year - 2009

Publication title -

antiviral chemistry and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.919

H-Index - 51

eISSN - 2040-2066

pISSN - 0956-3202

DOI - 10.3851/imp1286

Subject(s) - ns5b , replicon , biology , hepatitis c virus , aurintricarboxylic acid , rna dependent rna polymerase , virology , virus , biochemistry , enzyme , hepacivirus , polymerase , apoptosis , programmed cell death , plasmid , dna

Hepatitis C virus (HCV) NS5B is an essential component of the viral replication machinery and an important target for antiviral intervention. Aurintricarboxylic acid (ATA), a broad-spectrum antiviral agent, was evaluated and characterized for its anti-NS5B activity in vitro and in HCV replicon cells.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research