Open AccessRecent Advances in the Synthesis of Artificial Antigen and Its Application in the Detection of Pesticide Residue
Author(s) -
Dewen Tong,
Hee-Kyeong Yang,
Jinyi Wang
Publication year - 2007
Publication title -
american journal of agricultural and biological sciences
Language(s) - English
Resource type - Journals
eISSN - 1557-4997
pISSN - 1557-4989
DOI - 10.3844/ajabssp.2007.88.93
Subject(s) - residue (chemistry) , pesticide , pesticide residue , microbiology and biotechnology , chemistry , environmental science , biology , agronomy , biochemistry
Recent advances in the research of artificial antigen have shown that artificial antigens can be valuable approach for the treatment of some diseases as well as the detection of pesticide residues. By directly/indirectly coupling hapten to an appropriated carrier (macromolecule), artificial antigen can induce animals to produce hapten-specific antibody. Based on this principle, various vaccines have been developed. More impotently, new analytical method, immunological analysis has also been established. Comparing the conventional technologies, such as chromatographic methods, this promising method offers an alternative with high specificity, sensitivity, simplicity and suitability for the analysis of a large number of samples in a short period of time. In this review, we describe the recent advances in the synthesis of artificial antigen and its application in the detection of pesticide residues