Aldose reductase inhibition of the methanolic extracts of selected noxious and exotic plants | Zendy

Ju Sung Lee | Zendy; Dong Geon Woo | Zendy; Ga Eul Cho | Zendy; Sanghyun Lee | Zendy

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Aldose reductase inhibition of the methanolic extracts of selected noxious and exotic plants

Author(s) -

Ju Sung Lee,

Dong Geon Woo,

Ga Eul Cho,

Sanghyun Lee

Publication year - 2019

Publication title -

journal of applied biological chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.229

H-Index - 18

eISSN - 2234-7941

pISSN - 1976-0442

DOI - 10.3839/jabc.2019.028

Subject(s) - chemistry , aldose reductase , ic50 , traditional medicine , botany , biochemistry , enzyme , in vitro , biology , medicine

The inhibition of aldose reductase (AR) by the extracts from sixteen noxious and exotic plants was examined. Among them, Aster pilosus showed the highest inhibition of AR (IC50 value 0.11 μg/mL). This study showed that A. pilosus with promising AR-inhibitory activities can be utilized for the development of natural therapies for treating and managing diabetic complications.

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