Elicitor-treated extracts of Saururus chinensis inhibit the expression of inducible nitric oxide synthase and cyclooxygenase-2 enzyme expression in Raw cells for suppression of inflammation | Zendy

EunHo Lee | Zendy; HyeJin Park | Zendy; Dong Hee Kim | Zendy; HeeYoung Jung | Zendy; InKyu Kang | Zendy; YoungJe Cho | Zendy

Open Access

Elicitor-treated extracts of Saururus chinensis inhibit the expression of inducible nitric oxide synthase and cyclooxygenase-2 enzyme expression in Raw cells for suppression of inflammation

Author(s) -

EunHo Lee,

HyeJin Park,

Dong Hee Kim,

HeeYoung Jung,

InKyu Kang,

YoungJe Cho

Publication year - 2019

Publication title -

journal of applied biological chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.229

H-Index - 18

eISSN - 2234-7941

pISSN - 1976-0442

DOI - 10.3839/jabc.2019.021

Subject(s) - chemistry , nitric oxide synthase , elicitor , cyclooxygenase , nitric oxide , enzyme , biochemistry , inflammation , immunology , organic chemistry , biology

s Elicitor treatment was performed to increase the antiinflammatory activity of useful biological sources. The result showed that elicitor-treated Saururus chinensis leaf extracts positively affected nitric oxide (NO) production, and the expression of inducible NO synthase and cyclooxygenase-2 compared to extracts not exposed to elicitor treatment. This finding identified elicitor treatment as a suitable strategy for increasing the biological activity of S. chinensis. Therefore, elicitor-treated S. chinensis is useful both as health functional and medicinal materials.

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