Anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneata | Zendy

Jusung Lee | Zendy; Ah Young Lee | Zendy; Norman G. Quilantang | Zendy; Paul John L. Geraldino | Zendy; Eun Ju Cho | Zendy; Sanghyun Lee | Zendy

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Anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneata

Author(s) -

Jusung Lee,

Ah Young Lee,

Norman G. Quilantang,

Paul John L. Geraldino,

Eun Ju Cho,

Sanghyun Lee

Publication year - 2019

Publication title -

journal of applied biological chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.229

H-Index - 18

eISSN - 2234-7941

pISSN - 1976-0442

DOI - 10.3839/jabc.2019.020

Subject(s) - chemistry , isovitexin , scavenging , dpph , humin , antioxidant , nuclear chemistry , organic chemistry , flavonoid , fertilizer , humic acid , vitexin

This study evaluated the anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneata using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl (OH) scavenging assays. The results showed that among the four fractions, the highest OH radical scavenging activity was exhibited by the n-butanol fraction. The DPPH radical scavenging activities of avicularin and isovitexin were higher than 50% at a concentration of 100 μg/mL. Moreover, one hundred micrograms per liter of avicularin and isovitexin exhibited effective anti-oxidant activity, with the OH radical scavenging rates being 87.54 and 91.48%, respectively. These results suggest that Lespedeza cuneata would be useful anti-oxidant agents from natural sources.

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