Simultaneous determination of methoxyflavones in selected Korean thistles
Author(s) -
Joyce P. Rodriguez,
Norman G. Quilantang,
Ju Sung Lee,
Jun Yeon Park,
Jae Suk Shim,
Ki Sung Kang,
Eun Ju Cho,
Paul John L. Geraldino,
Sanghyun Lee
Publication year - 2018
Publication title -
journal of applied biological chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 18
eISSN - 2234-7941
pISSN - 1976-0442
DOI - 10.3839/jabc.2018.033
Subject(s) - chemistry , shim (computing) , audiology , medicine , erectile dysfunction
Simultaneous determination of three methoxyflavones, namely, cirsimarin (1), hispidulin (2), and cirsimaritin (3) in selected Korean thistles was performed via reversed-phase high performance liquid chromatography system. Compound 1 was present in all the thistle species examined, whereas 2 and 3 were only detected in Cirsium japonicum and C. japonicum var. maackii (CJM). The concentration of compounds 1-3 in CJM varied according to the time of harvest. Plants collected in the spring (CJMS) and fall (CJMF) had the highest contents of 3 and 1, respectively. A lower content of 2 was observed in CJMF than in CJMS. This indicates that seasonal variation affects the flavonoid content of CJM. The results of this study show that CJM is an excellent source of compounds 1-3 and it can potentially be cultivated for industrial and pharmaceutical applications involving these compounds.
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