Anti-inflammatory effect potentials of ethanol extracts from fermentatedCaryopteris incanabyLactobacillus plantarumon induced to LPS with Raw 264.7 cell | Zendy

Mi-Jeong Park | Zendy; HyeJin Park | Zendy; EunHo Lee | Zendy; HeeYoung Jung | Zendy; YoungJe Cho | Zendy

Open Access

Anti-inflammatory effect potentials of ethanol extracts from fermentatedCaryopteris incanabyLactobacillus plantarumon induced to LPS with Raw 264.7 cell

Author(s) -

Mi-Jeong Park,

HyeJin Park,

EunHo Lee,

HeeYoung Jung,

YoungJe Cho

Publication year - 2018

Publication title -

journal of applied biological chemistry

Language(s) - Spanish

Resource type - Journals

SCImago Journal Rank - 0.229

H-Index - 18

eISSN - 2234-7941

pISSN - 1976-0442

DOI - 10.3839/jabc.2018.021

Subject(s) - chemistry , lactobacillus plantarum , nitric oxide , ethanol , viability assay , lipopolysaccharide , fermentation , nitric oxide synthase , toxicity , food science , anti inflammatory , biochemistry , pharmacology , chromatography , cell , bacteria , lactic acid , immunology , biology , organic chemistry , genetics

L. plantarum 80% ethanol LPS Raw 264.7 cell . HPLC L. plantarum , profile . Raw 264.7 cell MTT assay , 80% ethanol 5, 10, 15 μg/mL 80% ethanol 10, 20, 30, 40 μg/mL 90.0% . iNOS , COX-2 , NO , PGE2 , pro-inflammatory cytokine . NO iNOS , 80% ethanol 15, 40 μg/mL 50.0% , . PGE2 COX-2 , 80% ethanol 15 μg/mL 50.0%, 80% ethanol 40 μg/mL 83.0% . NO 80% ethanal 15 μg/mL 62.0%, 40 μg/mL 81.0% control NO . PGE2 , 80% ethanal 15, 30 μg/mL 70.0% . , pro-inflammatory cytokine , 80% ethanol 15 μg/mL TNF-α 43.6%, IL-6 64.3%, IL-1β 58.7% , 80% ethanol 40 μg/mL TNF-α 75.4%, IL-6 64.3%, IL-1β 37.7% . , L. plantarum .

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