Assessment of human pluripotent stem cells with PluriTest | Zendy

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Assessment of human pluripotent stem cells with PluriTest

Author(s) -

Frank Müller

Publication year - 2014

Publication title -

stembook

Language(s) - English

Resource type - Journals

ISSN - 1940-3429

DOI - 10.3824/stembook.1.84.1

Subject(s) - induced pluripotent stem cell , biology , stem cell , somatic cell , embryonic stem cell , computational biology , microbiology and biotechnology , cell type , cellular differentiation , cell potency , genetics , cell , gene

Assessing pluripotency in human cells is inherently an intractable problem. In animal systems, pluripotency can be verified through direct means: pluripotent stem cells can be introduced into an developing embryo and thus the cellular developmental potential of any given in vitro preparation can be directly determined by observing the amount of chimaerism or viability of organisms partially or fully derived from in vitro stem cells (Nagy, Rossant et al., 1993: PMID8378314).

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