English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Objective: Starvation have pro-oxidative effect as a consequence of both elevated ROS generation and defeat in neutralization of ROS. Aloe vera juice induced oxidative stress and significantly decreased antioxidant enzymes levels. The main aim of this experiment was to evaluate the effect of Aloe vera gel extract on oxidative stress status during long period starvation Method: Twenty-four mature male albino Wistar rats were housed in standard cages. In this study starvation cycle (rats were starved for two days and then were fed for one day) was used. This study was performed during intermediate period (60 days).Animals were divided into four experimental groups (six rats in each group): 1) normal control; 2) starved rats + water/ethanol; 3) starved rats + hydro-alcoholic Aloe vera gel extract (100 mg/kg); 4) starved rats + hydro-alcoholic Aloe vera gel extract (200 mg/kg); 5) Without starvation with hydro-alcoholic Aloe Vera gel extract (100 mg/kg); 6) Without starvation with hydro-alcoholic Aloe Vera gel extract (200 mg/kg). Blood samples were obtained using cardiac puncture. In blood samples, antioxidant enzymes including SOD, GPx and catalase, antioxidant trace elements including copper, zinc and magnesium and antioxidant vitamins including vitamin A, vitamin E and vitamin C were measured Results: Plasma levels of antioxidant enzymes (SOD,GPX and catalase) significantly decreased in starved rats + water/ethanol group (P 0.05). Plasma levels of vitamin A and E in normal control group had no significant difference with starved rats + water/ethanol and starved rats + hydro-alcoholic Aloe vera gel extract in the 100 and 200 mg/kg dose groups (P > 0.05). Plasma level of vitamin C significantly decreased in starved rats + water/ethanol group (P < 0.05). Plasma level of vitamin C after treatment with hydro-alcoholic Aloe vera gel extract at doses 100 and 200 mg/kg was significantly increased (P < 0.05). Also, plasma level of vitamin C in normal rats (without starvation)  after treatment with hydro-alcoholic Aloe vera gel extract at doses 100 and 200 mg/kg was significantly increased (P < 0.05) Conclusion: In concluding our results it is shown that intermediate period starvation caused  an increase in oxidative stress via impairing of antioxidant defense and Aloe vera treatment is able  to improve antioxidative defense induced by starvation

Long Period Starvation in Rat: The Effect of Aloe Vera Gel Extract on Oxidative Stress Status