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Plague is a globally distributed, zoonotic disease caused by the bacterium  Yersinia pestis. With recurrent epidemics since the Antique, the plague ravaged the population, producing demographic, political, cultural and religious incommensurables effects. The major clinical forms of plague are bubonic, pneumonic, and septic. The signals and symptoms include fever, chills, general malaise, buboes, may evolve to septicemia, meningitis, hemorrhages, disseminate intravascular coagulation, shock and, not rarely, death. It can occur, still, lung infection (pneumonic form of the disease), with severe respiratory condition, fever, dyspnea, also leading to death.

Bubonic Plague: a brief history of changes to current situation in Brazil