BRCA1/2 mutations, including large genomic rearrangements, among unselected ovarian cancer patients in Korea | Zendy

DoHoon Kim | Zendy; ChiHeum Cho | Zendy; Sun Young Kwon | Zendy; Nam Hee Ryoo | Zendy; DongSeok Jeon | Zendy; Wonmok Lee | Zendy; JungSook Ha | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

BRCA1/2 mutations, including large genomic rearrangements, among unselected ovarian cancer patients in Korea

Author(s) -

DoHoon Kim,

ChiHeum Cho,

Sun Young Kwon,

Nam Hee Ryoo,

DongSeok Jeon,

Wonmok Lee,

JungSook Ha

Publication year - 2018

Publication title -

journal of gynecologic oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.358

H-Index - 37

eISSN - 2005-0399

pISSN - 2005-0380

DOI - 10.3802/jgo.2018.29.e90

Subject(s) - multiplex ligation dependent probe amplification , sanger sequencing , medicine , ovarian cancer , oncology , breast cancer , mutation , cancer , nonsense mutation , cancer research , bioinformatics , genetics , biology , gene , missense mutation , exon

Twenty-two (16.8%) of the unselected ovarian cancer patients had mutations that were detected through comprehensive genetic testing. Ovarian cancer patients with Sanger-negative results should be considered for LGR detection if they have one blood relative with breast or ovarian cancer. The detection of more mutations in patients is important for efforts to provide targeted therapy to ovarian cancer patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research