Perioperative changes in serum CA125 levels: a prognostic factor for disease-specific survival in patients with ovarian cancer | Zendy

Nienke Zwakman | Zendy; Rafli van de Laar | Zendy; Toon Van Gorp | Zendy; Petra L.M. Zusterzeel | Zendy; Marc P.L.M. Snijders | Zendy; Isabel Ferreira | Zendy; Leon F.A.G. Massuger | Zendy; Roy F.P.M. Kruitwagen | Zendy

Open Access

Perioperative changes in serum CA125 levels: a prognostic factor for disease-specific survival in patients with ovarian cancer

Author(s) -

Nienke Zwakman,

Rafli van de Laar,

Toon Van Gorp,

Petra L.M. Zusterzeel,

Marc P.L.M. Snijders,

Isabel Ferreira,

Leon F.A.G. Massuger,

Roy F.P.M. Kruitwagen

Publication year - 2016

Publication title -

journal of gynecologic oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.358

H-Index - 37

eISSN - 2005-0399

pISSN - 2005-0380

DOI - 10.3802/jgo.2017.28.e7

Subject(s) - medicine , perioperative , ovarian cancer , oncology , cancer , disease , surgery

The current study, although hampered by possible biases, suggests that the perioperative decline in serum CA125 is an early biomarker that predicts disease-specific survival in patients who underwent primary cytoreductive surgery for advanced stage EOC. If confirmed prospectively, the perioperative change in serum CA125 could be a better marker for residual tumor volume after primary cytoreductive surgery (and therewith disease-specific survival) than the surgeons' estimation of residual tumor volume.

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