Adult granulosa cell tumors of the ovary: a retrospective study of 30 cases with respect to the expression of steroid synthesis enzymes | Zendy

Sachiko Kitamura | Zendy; Kaoru Abiko | Zendy; Noriomi Matsumura | Zendy; Hidekatsu Nakai | Zendy; Yumiko Akimoto | Zendy; H Tanimoto | Zendy; Ikuo Konishi | Zendy

Open Access

Adult granulosa cell tumors of the ovary: a retrospective study of 30 cases with respect to the expression of steroid synthesis enzymes

Author(s) -

Sachiko Kitamura,

Kaoru Abiko,

Noriomi Matsumura,

Hidekatsu Nakai,

Yumiko Akimoto,

H Tanimoto,

Ikuo Konishi

Publication year - 2017

Publication title -

journal of gynecologic oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.358

H-Index - 37

eISSN - 2005-0399

pISSN - 2005-0380

DOI - 10.3802/jgo.2017.28.e31

Subject(s) - medicine , aromatase , hormone , granulosa cell , endocrinology , endometrial hyperplasia , estrogen , ovary , theca , endometrial cancer , follicle stimulating hormone , hyperplasia , cancer , breast cancer , luteinizing hormone

The expression of hormone-synthesizing enzymes divides granulosa cell tumors into 2 distinct types; tumors with P450c17-positive cells show elevated serum E₂ and related clinical symptoms, while tumors without these cells show symptoms related to FSH suppression by inhibin.

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