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Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Author(s) -
Bradford Z. Mahon,
Jeffrey A. Mead,
Benjamin L. Chernoff,
Maxwell H. Sims,
Frank E. Garcea,
Emily Prentiss,
Raouf Belkhir,
Sam Haber,
Sarah B. Gan,
Steve Erickson,
Kelly A. Wright,
Michael Z. Schmidt,
Audrey Paulzak,
Vanessa Milano,
David A. Paul,
Kenneth Foxx,
Madalina E. Tivarus,
Jacob W. Nadler,
Jacqueline M Behr,
Susan O. Smith,
Yan Michael Li,
Kevin A. Walter,
Webster H. Pilcher
Publication year - 2019
Publication title -
journal of visualized experiments
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 91
ISSN - 1940-087X
DOI - 10.3791/59592
Subject(s) - workflow , translational research , neurosurgery , cognition , outcome (game theory) , brain mapping , neuroscience , medicine , translational science , medical physics , psychology , computer science , surgery , pathology , mathematics , mathematical economics , database
The Translational Brain Mapping Program at the University of Rochester is an interdisciplinary effort that integrates cognitive science, neurophysiology, neuroanesthesia, and neurosurgery. Patients who have tumors or epileptogenic tissue in eloquent brain areas are studied preoperatively with functional and structural MRI, and intraoperatively with direct electrical stimulation mapping. Post-operative neural and cognitive outcome measures fuel basic science studies about the factors that mediate good versus poor outcome after surgery, and how brain mapping can be further optimized to ensure the best outcome for future patients. In this article, we describe the interdisciplinary workflow that allows our team to meet the synergistic goals of optimizing patient outcome and advancing scientific understanding of the human brain.

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