Blood Collection Through Subclavian Vein Puncture in Mice | Zendy

Hui Yang | Zendy; Chenlu Wu | Zendy; Fengjiao Liu | Zendy; Mi Wang | Zendy; Pu Zou | Zendy; Yuhu He | Zendy; Qiming Liu | Zendy; Qin Zhou | Zendy; Shenghua Zhou | Zendy

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Blood Collection Through Subclavian Vein Puncture in Mice

Author(s) -

Hui Yang,

Chenlu Wu,

Fengjiao Liu,

Mi Wang,

Pu Zou,

Yuhu He,

Qiming Liu,

Qin Zhou,

Shenghua Zhou

Publication year - 2019

Publication title -

journal of visualized experiments

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.596

H-Index - 91

ISSN - 1940-087X

DOI - 10.3791/59556

Subject(s) - blood collection , tail vein , vein , medicine , human blood , subclavian vein , data collection , surgery , pathology , emergency medicine , biology , physiology , in vivo , catheter , statistics , microbiology and biotechnology , mathematics

The mouse is the foremost mammalian model for studying human disease and human health. However, blood sample collection from mice is challenging in research work. Tail blood collection is a popular method when a small amount of blood sample is needed. Orbital artery could be considered if a large amount of blood is needed but this blood collection method has ethical issues. Formerly, we demonstrated the feasibility and safety of blood sample collection through subclavian vein puncture in rats, and here we investigate whether this method could be used in mice. We report that this method is safe and practical for blood collection in mice. Blood collection through the subclavian vein puncture in mice can be a convenient method in daily research works.

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