Reconstruction of 3D light distribution produced by cylindrical diffuser in deep tissues based on photoacoustic imaging
Author(s) -
Wenming Xie,
Yubin Liu,
Zhifang Li,
Hui Li
Publication year - 2014
Publication title -
chinese optics letters
Language(s) - English
Resource type - Journals
ISSN - 1671-7694
DOI - 10.3788/col201412.051702
Subject(s) - diffuser (optics) , photoacoustic imaging in biomedicine , optics , materials science , integral imaging , photoacoustic tomography , light source , physics , computer science , artificial intelligence , image (mathematics)
Measurement of light distribution in biological tissue contributes to selecting strategy and optimizing dose for biomedical application. In this letter, a photoacoustic method combined with Monte Carlo simulation was used to estimate the three-dimensional light distribution in biological tissue. The light distribution was produced by a cylindrical diffuser which interposed into tissues. The light profiles obtained by the method were compared to those detected by photo diodes. The experimental results demonstrate the feasibility of this method. The approach can play a significant role for photo-dosimetry in biomedical phototherapy.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom