Determination of an Antiviral Activity of a Composition Comprising Glutathione Reductase (GSSG-R) and Oxidized Glutathione (GSSG) for Pharmaceutical use: Experiments In vitro and In vivo | Zendy

Raffaele Ansovini | Zendy

Open Access

Determination of an Antiviral Activity of a Composition Comprising Glutathione Reductase (GSSG-R) and Oxidized Glutathione (GSSG) for Pharmaceutical use: Experiments In vitro and In vivo

Author(s) -

Raffaele Ansovini

Publication year - 2020

Publication title -

journal of biomedical research and environmental sciences

Language(s) - English

Resource type - Journals

ISSN - 2766-2276

DOI - 10.37871/jels1117

Subject(s) - glutathione , glutathione reductase , glutathione disulfide , biochemistry , chemistry , in vivo , glutaredoxin , cell , in vitro , enzyme , biology , glutathione peroxidase , microbiology and biotechnology

There are several viruses that are not currently covered by efficient antiviral terapies, as towards Poliovirus and the new Covid19. The spread of atypical viral strains strongly raises the need of having efficient terapies with wide coverage against viruses. In the following experiments it was used a composition comprising Glutathione Reductase (GSSG-r) and Oxidized Glutathione (GSSG), which we call GR compound, for pharmaceutical use as antiviral, in vitro, towards RNA nad DNA virus, and in vivo towards a Swine Flu Virus (H1N1) adapted to the mouse .

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