English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Hepatitis E virus (HEV) is transmitted through a fecal-oral route[1]. HEV induces acute hepatitis and is responsible for a significant portion of the fulminant hepatitis in epidemic and sporadic cases, especially in the mixed infection patients and women in their third trimester of pregnancy[1]. It has been reported that HEV infection is more prevalent in underdeveloped and develo ping countries in Asia, Africa, and Central America, but is rare in developed countries[1]. In China, a large outbreak occurred between 1986 and 1988 in Xinjiang, and sporadic spread was often found in other regions.  HEV is a non-enveloped virus, approximately 27 nm-34 nm in diameter and has a positive-sense, single-stranded RNA genome of approximately 7.2 kb. The viral genome consists of three discontinuous open reading frames (ORFs). Since the molecular cloning and sequencing of HEV were described[2], several genomic analyses of HEV strains obtained from different geographic areas have been reported[3]. The existing variations on the gene structure of HEV strains from some regions of China was reported by us[4]. In this study, after the collection of the serum samples of patients with acute hepatitis in Xiamen, anti-HEV antibody and HEV RNA in serum were detected, further HEV RNA was cloned and sequenced. The results are described and discussed.

Antibody detection and sequence analysis of sporadic HEV in Xiamen region