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Clinical significance of changes of perioperative T cell and expression of its activatedantigen in colorectal cancer patients
Author(s) -
Yixin Wang
Publication year - 1999
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v5.i2.181
Subject(s) - colorectal cancer , medicine , perioperative , clinical significance , oncology , cancer , gastroenterology , cancer research , surgery
Immune function status is corresponded to genesis and progress of tumor, and cell immune plays a major role in anti-tumor immunity. In recent years, there has been more and more interest in the effect of tumor on functional imbalance of T lymphocyte subgroups. In order to study changes of immune status in colorectal cancer patients before and after operation, we determined six kinds of T lymphocyte surface antigens including CD3, CD4, CD8, CD16, CD69 and CD3+/HLA-DR+ in 35 patients with colorectal cancer from April 1996 to March 1997, and the results were compared with those in patients with benign diseases.

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