Relation of atrophic gastritis with Helicobacter pylori -CagA+ and interleukin-1 gene polymorphisms
Author(s) -
Rafaela Sierra,
Clas Une,
Vanessa Ramírez,
Warner AlpízarAlpízar,
Isabel González,
José A Ramírez,
Antoine de Mascarel,
Patricia Cuenca,
Guillermo I. PérezPérez,
Françis Mégraud
Publication year - 2008
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.14.6481
Subject(s) - caga , helicobacter pylori , gastroenterology , rapid urease test , atrophic gastritis , population , gastritis , medicine , genotyping , genotype , immunology , biology , gene , genetics , virulence , environmental health
To determine the association of Helicobacter pylori (H pylori) CagA(+) infection and pro-inflammatory polymorphisms of the genes interleukin (IL)-1RN and IL-1B with the risk of gastric atrophy and peptic ulcers in a dyspeptic population in Costa Rica, a country with high incidence and mortality of gastric cancer.
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