Clinical Significance of Epithelial–Mesenchymal Transition–Related Molecules in Lung Adenocarcinoma | Zendy

Yu Zhang | Zendy; Lisha Wang | Zendy; JingWei Gao | Zendy; L. Li | Zendy; Pan Jiang | Zendy; Xin Lv | Zendy; Lixia Yu | Zendy; Jianwei Yang | Zendy; Rutian Li | Zendy; B R Liu | Zendy

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Clinical Significance of Epithelial–Mesenchymal Transition–Related Molecules in Lung Adenocarcinoma

Author(s) -

Yu Zhang,

Lisha Wang,

JingWei Gao,

L. Li,

Pan Jiang,

Xin Lv,

Lixia Yu,

Jianwei Yang,

Rutian Li,

B R Liu

Publication year - 2019

Publication title -

current oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.053

H-Index - 51

eISSN - 1718-7729

pISSN - 1198-0052

DOI - 10.3747/co.26.4471

Subject(s) - medicine , epithelial–mesenchymal transition , adenocarcinoma , lung , mesenchymal stem cell , clinical significance , transition (genetics) , pathology , cancer research , cancer , biology , metastasis , genetics , gene

Epithelial-mesenchymal transition (emt) refers to the biologic process in which epithelial cells are transformed into interstitial phenotypes by specific pathways. This transition plays an important biologic role in the process by which epithelium-derived malignant tumour cells acquire the ability to migrate and invade. We explored the relationship between emt-associated molecules and patient-related clinical factors to determine whether any clinical characteristics could be used as biomarkers for emt-related protein alterations in lung cancer-especially lung adenocarcinoma.

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