Genetic Polymorphisms of Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor Binding Protein 3, Xenoestrogen, Phytoestrogen, and Premenopausal Breast Cancer | Zendy

Hui Li | Zendy; Min Zhao | Zendy; Q. Wang | Zendy; L. Liu | Zendy; Yana Qi | Zendy; Junying Li | Zendy

Open Access

Genetic Polymorphisms of Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor Binding Protein 3, Xenoestrogen, Phytoestrogen, and Premenopausal Breast Cancer

Author(s) -

Hui Li,

Min Zhao,

Q. Wang,

L. Liu,

Yana Qi,

Junying Li

Publication year - 2016

Publication title -

current oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.053

H-Index - 51

eISSN - 1718-7729

pISSN - 1198-0052

DOI - 10.3747/co.23.2835

Subject(s) - medicine , odds ratio , breast cancer , insulin like growth factor , igfbp3 , confidence interval , logistic regression , case control study , genotype , endocrinology , risk factor , oncology , cancer , growth factor , biology , genetics , gene , receptor

Previous studies suggest a combined effect of insulin-like growth factor 1 (igf-1) and igf binding protein 3 (igfbp-3) gene polymorphisms, xenoestrogen, and phytoestrogen on the igf-1 signalling pathway and serum concentrations in the igf system, which are associated with premenopausal breast cancer (bca) risk.

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