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Previous studies suggest a combined effect of insulin-like growth factor 1 (igf-1) and igf binding protein 3 (igfbp-3) gene polymorphisms, xenoestrogen, and phytoestrogen on the igf-1 signalling pathway and serum concentrations in the igf system, which are associated with premenopausal breast cancer (bca) risk.

current oncology

Genetic Polymorphisms of Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor Binding Protein 3, Xenoestrogen, Phytoestrogen, and Premenopausal Breast Cancer