Well-functioning cell mitochondria promote good health
Author(s) -
Winyoo Chowanadisai,
Sonia F Shenoy,
Edward Sharman,
Carl L. Keen,
Jiankang Liu,
Robert B. Rucker
Publication year - 2011
Publication title -
california agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.472
H-Index - 25
eISSN - 2160-8091
pISSN - 0008-0845
DOI - 10.3733/ca.v065n03p136
Subject(s) - mitochondrion , downregulation and upregulation , antioxidant , function (biology) , beta oxidation , metabolism , microbiology and biotechnology , cell , disease , biochemistry , inflammation , biology , chemistry , medicine , gene , immunology
Mitochondriol function can be directly linked to protection from certain chronic diseases and conditions, such as heart disease, diabetes, metabolic syndrome and chronic inflammation, as well as the aging processes. Mitochondria are central to normal glucose, amino acid and fatty acid metabolism, in addition to antioxidant modulation and virtually all aspects of cell turnover and maintenance. Nutrition plays an essential role in optimizing such functions. We describe strategies for the regulation of mitochondria, as well as metabolic strategies for dealing with the thousands of compounds in plants and animal tissues that are metabolically important. Many of these compounds function to signal the up- or downregulation of mitochondria or act as antioxidants.
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