Development of molecularly imprinted microextraction techniques

Microextraction techniques can extract efficiently the analytes from a sample matrix to the polymers or organic solvents of microvolume, and integrate sampling, extraction, concentration and injection into one single step. They have the advantages of simple, time-efficient and solvent-free. They have been successfully coupled with a variety of analytical tools, such as gas chromatography and high performance liquid chromatography. Molecularly imprinted polymers have specific recognition ability. They can separate and enrich analytes from complicated matrix with high selectivity, and they have great application prospects in complicated sample preparation. This review summarizes the progress in the molecularly imprinted microextraction techniques, including molecularly imprinted-solid phase microextraction, molecularly imprinted-stir bar adsorptive extraction, magnetic molecularly imprinted beads extraction, etc. A total of 75 references are cited.