Association between chicken A-FABP gene polymorphisms and growth and body composition traits | Zendy

Qigui Wang | Zendy; Tianzhu Guan | Zendy; Shouzhi Wang | Zendy; Hui Zhang | Zendy; Zhipeng Wang | Zendy; Hui Li | Zendy

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Association between chicken <I>A-FABP</I> gene polymorphisms and growth and body composition traits

Author(s) -

Qigui Wang,

Tianzhu Guan,

Shouzhi Wang,

Hui Zhang,

Zhipeng Wang,

Hui Li

Publication year - 2011

Publication title -

hereditas (beijing)

Language(s) - English

Resource type - Journals

ISSN - 0253-9772

DOI - 10.3724/sp.j.1005.2011.00153

Subject(s) - biology , broiler , linkage disequilibrium , single nucleotide polymorphism , haplotype , genetics , restriction fragment length polymorphism , genetic association , candidate gene , population , gene , allele , zoology , genotype , medicine , environmental health

This experiment was designed to study the effects of polymorphism of A-FABP gene on growth and body composition traits in chicken. The 10th generation broiler population, derived from the Northeast Agricultural University broiler lines divergently selected for abdominal fat content (NEAUHLF) was used. Polymorphism among individuals was detected by DNA sequencing, PCR-RFLP, PCR-LP, and DHPLC. Linkage disequilibrium analysis for eight SNPs was performed, and five htSNPs were selected to construct haplotypes. The association analysis between the individual SNPs and haplotypes and growth and body composition traits were investigated, respectively. The results showed that there were consistently significant effects on muscle stomach weight (MSW) and percentage of muscle stomach (MSW/BW) (Pamp;0.05) in the seven SNPs (except for SNP 5) and haplotypes, but no significant effect on any other trait (P>0.05). Due to no evidence on effects of A-FABP for digestion system in other species, future experiments need to be developed to confirm whether A-FABP could be a major gene of MSW and MSW/BW traits in broiler chicken.

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