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Q (Query) fever is a zoonotic illness caused by the bacterium Coxiella burnetti, which is transmitted to humans via host animals, usually cattle, sheep and goats. Acute Q fever often presents as a flu-like illness or atypical pneumonia that is nonspecific and often self-limiting. The identification of acute infection is clinically important due to the high morbidity and mortality associated with chronic infection. We present a case of a 43-year-old female who lived in the vicinity of cattle and goats and presented with an acute febrile illness found to be secondary to acute Q fever infection. Exposure to Q fever in the United States is frequently not associated with a classical occupational exposure and should be considered in those living in areas near to possible host animals. We discuss clinical presentation and clues to diagnosis, as well as relevant epidemiology. This case highlights important considerations for risk stratification for chronic infection and follow-up in acute Q fever patients.

A Case of Acute Fever with Thrombocytopenia: Diagnostic and Clinical Review of Acute Q Fever Infections